DL-Panthenol (Powder): –
CAS Number: – 16485-10-2
What it is
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INCI Name: Panthenol
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Form: White crystalline powder (hygroscopic, water-soluble)
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Type: Racemic mixture of D- and L-isomers (DL-form)
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Pro-vitamin B5: Converts into pantothenic acid (Vitamin B5) in the skin and hair.
Functions in Cosmetics
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Moisturizing Agent – strong humectant, binds and retains water in skin and hair.
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Conditioning Agent – improves hair elasticity, softness, and shine.
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Soothing & Healing – reduces redness, irritation, and supports skin barrier repair.
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Film-Former – forms a smooth, protective layer on skin and hair.
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Improves Product Stability – helps stabilize emulsions in creams and lotions.
Applications
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Skin Care: Creams, lotions, serums, gels, masks.
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Hair Care: Shampoos, conditioners, leave-on treatments, hair masks.
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Nail Care: Strengthening polishes and treatments.
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Sun & After-sun Care: Soothing gels, sunscreens.
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Baby Care: Mild creams, lotions, wipes due to its soothing properties.
Benefits
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Deep hydration and prevention of transepidermal water loss (TEWL).
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Enhances wound healing and reduces inflammation.
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Provides shine, reduces split ends, and strengthens hair.
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Non-irritating, suitable for sensitive skin formulations.
Formulation Notes
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Usage Level: Typically 0.5 – 5% (commonly 1–2%).
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Solubility: Easily soluble in water, alcohol, and propylene glycol.
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Stability: Stable across a wide pH range (4–7); may degrade at high temperatures (add below 70°C).
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Compatibility: Works well with other humectants (glycerin, hyaluronic acid) and conditioning agents.
Summary:
DL-Panthenol (powder) is a versatile, water-soluble pro-vitamin B5 widely used in skin, hair, and nail care formulations for its moisturizing, soothing, and conditioning properties. It is highly valued in personal care and cosmetics for improving hydration, softness, and overall skin & hair health.

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